Apolipoprotein B is regulated by gonadotropins and constitutes a predictive biomarker of IVF outcomes.
Fiche publication
Date publication
mai 2016
Journal
Reproductive biology and endocrinology : RB&E
Auteurs
Membres identifiés du Cancéropôle Est :
Pr DUVILLARD Laurence
Tous les auteurs :
Scalici E, Bechoua S, Astruc K, Duvillard L, Gautier T, Drouineaud V, Jimenez C, Hamamah S
Lien Pubmed
Résumé
Follicular fluid (FF) is an important micro-environment influencing oocyte growth, its development competence, and embryo viability. The FF content analysis allows to identify new relevant biomarkers, which could be predictive of in vitro fertilization (IVF) outcomes. Inside ovarian follicle, the amount of FF components from granulosa cells (GC) secretion, could be regulated by gonadotropins, which play a major role in follicle development.
Mots clés
Adult, Apolipoproteins B, metabolism, Biomarkers, metabolism, Chorionic Gonadotropin, therapeutic use, Embryo, Mammalian, Embryonic Development, Female, Fertilization, Fertilization in Vitro, Follicle Stimulating Hormone, therapeutic use, Follicular Fluid, metabolism, Granulosa Cells, metabolism, Humans, Oocyte Retrieval, Ovulation Induction, Prospective Studies, Treatment Outcome
Référence
Reprod. Biol. Endocrinol.. 2016 May;14(1):28