Stretch-induced Activation of Transforming Growth Factor-β1 in Pulmonary Fibrosis.
Fiche publication
Date publication
juillet 2016
Journal
American journal of respiratory and critical care medicine
Auteurs
Membres identifiés du Cancéropôle Est :
Dr BELLAYE Pierre-Simon
Tous les auteurs :
Froese AR, Shimbori C, Bellaye PS, Inman M, Obex S, Fatima S, Jenkins G, Gauldie J, Ask K, Kolb M
Lien Pubmed
Résumé
Recent findings suggesting transforming growth factor (TGF)-β1 activation by mechanical stimuli in vitro raised the question of whether this phenomenon was relevant in vivo in the context of pulmonary fibrosis.
Mots clés
mechanical stress, mechanotransduction, pulmonary fibrosis, transforming growth factor-β1, ventilation
Référence
Am. J. Respir. Crit. Care Med.. 2016 07 1;194(1):84-96