[Radiotherapy for brain metastases].
Fiche publication
Date publication
septembre 2016
Journal
Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
Auteurs
Membres identifiés du Cancéropôle Est :
Pr ANTONI Delphine, Pr NOEL Georges, Pr TRUC Gilles
Tous les auteurs :
Latorzeff I, Antoni D, Gaudaire-Josset S, Feuvret L, Tallet-Richard A, Truc G, Noël G
Lien Pubmed
Résumé
Radiotherapy for brain metastases has become more multifaceted. Indeed, with the improvement of the patient's life expectancy, side effects must be undeniably avoided and the retreatments or multiple treatments are common. The cognitive side effects should be warned and the most modern techniques of radiation therapy are used regularly to reach this goal. The new classifications of patients with brain metastases help guiding treatment more appropriately. Stereotactic radiotherapy has supplanted whole brain radiation therapy both for patients with metastases in place and for those who underwent surgery. Hippocampus protection is possible with intensity-modulated radiotherapy. Its relevance in terms of cognitive functioning should be more clearly demonstrated but the requirement, for using it, is increasingly strong. While addressing patients in palliative phase, the treatment of brain metastases is one of the localisations where technical thinking is the most challenging.
Mots clés
Age Factors, Brain, radiation effects, Brain Neoplasms, radiotherapy, Cognition Disorders, etiology, Combined Modality Therapy, Cranial Irradiation, adverse effects, Dose Fractionation, Humans, Organs at Risk, Radiation Injuries, prevention & control, Radiosurgery, adverse effects, Radiotherapy Dosage, Radiotherapy Planning, Computer-Assisted, Radiotherapy, Intensity-Modulated, adverse effects
Référence
Cancer Radiother. 2016 Sep;20 Suppl:S80-7