Let us not underestimate the long-term risk of SPLC after surgical resection of NSCLC.

Fiche publication


Date publication

septembre 2019

Journal

Lung cancer (Amsterdam, Netherlands)

Auteurs

Membres identifiés du Cancéropôle Est :
Pr ADOTEVI Olivier, Pr FALCOZ Pierre-Emmanuel, Pr WESTEEL Virginie, Dr WORONOFF Anne-Sophie


Tous les auteurs :
Leroy T, Monnet E, Guerzider S, Jacoulet P, De Bari B, Falcoz PE, Gainet-Brun M, Lahourcade J, Alfreijat F, Almotlak H, Adotevi O, Pernet D, Polio JC, Desmarets M, Woronoff AS, Westeel V

Résumé

Several studies have reported that patients operated on for non-small cell lung cancer (NSCLC) are at high risk of second primary lung cancer (SPLC). However, widely varying estimates of this risk have been reported, with very few studies taking into account that these patients are at particularly high competing risk of death, due to recurrence of the initial disease and to comorbidities. Risk factor evaluation over time has significant repercussions on the post-surgery surveillance strategy offered for NSCLC. This study primarily sought to measure the risk of SPLC in a long-term follow-up series, using statistical methods considering competing risks of death.

Mots clés

Follow-up, Non-small cell lung cancer, Postoperative radiotherapy, Second primary lung cancer, Surgery

Référence

Lung Cancer. 2019 Sep 3;137:23-30