[Hyper-IgE in internal medicine].
Fiche publication
Date publication
mai 2018
Journal
La Revue de medecine interne
Auteurs
Membres identifiés du Cancéropôle Est :
Dr DEVILLIERS Hervé, Pr BONNIAUD Philippe
Tous les auteurs :
Devilliers H, Turcu A, Vernier N, Muller G, Bielefeld P, Bonniaud P, Besancenot JF
Lien Pubmed
Résumé
Hyper-IgE may be found under many pathological conditions. The role of IgE is essentially associated with the occurrence of allergic manifestations, which may be accompanied by an increase of their serum levels. Elevation of total IgE has also been reported in association with certain rare genetic immune deficiencies called hyper-IgE syndromes. Other circumstances such as infectious diseases, tumors or autoimmune diseases may also be accompanied by an excessive synthesis of IgE. Considering the diversity of these situations, discussion of the prognostic value of total IgE is useful to the internist.
Mots clés
Allergie, Allergy, Balance cytokines Th1-Th2, IgE, Job-Buckley syndrome, Syndrome de Job-Buckley, Th1-Th2 Cytokine Balance
Référence
Rev Med Interne. 2018 May;39(5):332-338