Bone marrow necrosis and human parvovirus associated infection preceding an Ph1+ acute lymphoblastic leukemia.
Fiche publication
Date publication
novembre 1992
Journal
Leukemia & lymphoma
Auteurs
Membres identifiés du Cancéropôle Est :
Dr CAILLOT Denis
Tous les auteurs :
Petrella T, Bailly F, Mugneret F, Caillot D, Chavanet P, Guy H, Solary E, Waldner A, Devilliers E, Carli PM
Lien Pubmed
Résumé
A case of bone marrow necrosis associated with a serologically documented recent Parvovirus B 19 infection which preceded the development of PH1+ acute lymphoblastic leukemia is reported. No conclusions can be drawn on the basis of a single case but the question of the role of human Parvovirus B19 in the pathogenesis of bone marrow necrosis is discussed. It is suggested that the virus may act as a co-factor for the induction of bone marrow necrosis, in some cases.
Mots clés
Adult, Antineoplastic Combined Chemotherapy Protocols, therapeutic use, Bone Marrow, pathology, Cyclophosphamide, administration & dosage, Daunorubicin, administration & dosage, Erythema Infectiosum, complications, Female, Humans, Karyotyping, Methotrexate, administration & dosage, Pancytopenia, etiology, Parvovirus B19, Human, pathogenicity, Philadelphia Chromosome, Precursor Cell Lymphoblastic Leukemia-Lymphoma, complications, Prognosis, Remission Induction, Steroids, administration & dosage, Vincristine, administration & dosage
Référence
Leuk. Lymphoma. 1992 Nov;8(4-5):415-9