The cell nucleus. A study in Burgundy.
Fiche publication
Date publication
décembre 2019
Journal
Nucleus (Austin, Tex.)
Auteurs
Membres identifiés du Cancéropôle Est :
Dr DEMIDOV Oleg
Tous les auteurs :
Demidov O, Aksenova V, Dasso M, Arnaoutov A
Lien Pubmed
Résumé
Wilhelm Bernhard's revolutionary microscopy techniques helped him put forward the hypothesis of specialized compartmentalization of the nucleus. He also described for the first time the nuclear bodies and peri-chromatin fibrils, and demonstrated that these granules contain an RNA component. The tradition of biennial workshops, named after this great scientist, continues, and this year it took place in the heart of Burgundy, in Dijon, France (May 20-24, 2019, organized by INSERM UMR1231, UBFC), where well-fed participants emphasized the importance of viewing the cell nucleus as a hub of specialized colloidal compartments that orchestrate replication, transcription and nuclear transport.
Mots clés
Phase separation, lamins, nuclear pores, nucleolus
Référence
Nucleus. 2019 Dec;10(1):213-217