The Ribosome Holds the RNA Polymerase on Track in Bacteria.
Fiche publication
Date publication
septembre 2017
Journal
Trends in biochemical sciences
Lien Pubmed
Résumé
The central dogma of molecular biology comprises two fundamental mechanistic steps of gene expression (transcription and translation), which, in bacteria, are coupled. A recent study provides structural insights into a supercomplex between the RNA polymerase and the ribosome, thus highlighting the synergy between two key macromolecular machineries in the cell.
Mots clés
RNA polymerase, bacteria, gene expression, ribosome, transcription, translation
Référence
Trends Biochem. Sci.. 2017 09;42(9):686-689