Familial small-intestine carcinoids: Chromosomal alterations and germline inositol polyphosphate multikinase sequencing.

Date publication

janvier 2017

Journal

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

Auteurs

Membres identifiés du Cancéropôle Est :
Pr CADIOT Guillaume

Tous les auteurs :
de Mestier L, Pasmant E, Fleury C, Brixi H, Sohier P, Féron T, Diebold MD, Clauser E, Cadiot G,

Lien Pubmed

http://www.ncbi.nlm.nih.gov/pubmed/27825921

Résumé

Familial small-intestine neuroendocrine tumors (SI-NETs) are an exceptional inherited entity. Underlying predisposing mechanisms are unelucidated, but inositol polyphosphate multikinase (IPMK) gene alterations might promote their tumorigenesis.

Référence

Dig Liver Dis. 2017 Jan;49(1):98-102