CETP activity is not associated with carotid intima-media thickness in patients with poorly controlled type 2 diabetes.

Fiche publication


Date publication

avril 2019

Journal

Acta diabetologica

Auteurs

Membres identifiés du Cancéropôle Est :
Dr LAGROST Laurent, Pr PETIT Jean-Michel, Pr VERGES Bruno


Tous les auteurs :
Bouillet B, Gautier T, Terriat B, Lagrost L, Verges B, Petit JM

Résumé

The impact of cholesteryl ester transfer protein (CETP) on atherosclerotic development in humans remains unclear. Plasma cholesteryl ester transfer was shown to be associated with carotid intima-media thickness in type 2 diabetic (T2D) patients with adequate metabolic control. Since glycation of CETP may influence cholesteryl ester transfer processes, it is important to determine if plasma cholesteryl ester transfer is still a determinant of carotid intima-media thickness (IMT) in patients with poorly controlled diabetes. The aim of the present study was to determine whether CETP activity influences carotid IMT in T2D patients with poor metabolic control.

Mots clés

Cholesteryl ester transfer protein, Intima-media thickness, Type 2 diabetes

Référence

Acta Diabetol. 2019 Apr 12;: