Interest of studying the saliva metabolome, transcriptome and microbiome in screening for pancreatic cancer.
Fiche publication
Date publication
avril 2019
Journal
Journal of stomatology, oral and maxillofacial surgery
Auteurs
Membres identifiés du Cancéropôle Est :
Pr ZWETYENGA Narcisse
Tous les auteurs :
Sturque J, Berquet A, Loison-Robert LS, Ahossi V, Zwetyenga N
Lien Pubmed
Résumé
Pancreatic cancer is a public health problem because its mortality rate is close to its incidence rate. If it were possible to detect this cancer before the onset of symptoms, 5-year survival could reach 75%. Numerous studies have attempted to accelerate the diagnosis to improve survival. Saliva presents interesting characteristics as a fluid for screening and diagnosis. Its many components provide a promising source of constitutive biomarkers with a specific signature of the disease. The aim of this work was to determine the interest of studying the metabolome, the transcriptome and the microbiome of saliva in screening for pancreatic cancer.
Mots clés
biomarkers, pancreatic neoplasm, saliva, screening
Référence
J Stomatol Oral Maxillofac Surg. 2019 Apr 26;: