Medical treatment of mammary desmoid-type fibromatosis: which benefit?
Fiche publication
Date publication
avril 2017
Journal
World journal of surgical oncology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr KURTZ Jean-Emmanuel, Pr MATHELIN Carole
Tous les auteurs :
Scheer L, Lodi M, Molière S, Kurtz JE, Mathelin C
Lien Pubmed
Résumé
Breast fibromatosis is a rare disease characterized by monoclonal fibroblast proliferation. It has no ability to metastasize but has a high local recurrence rate and often infiltrates surrounding tissues. Surgical treatment is the reference, but recently, new targeted therapies have emerged. We report an original case of a patient with breast fibromatosis who received exclusive medical treatment. Our aim was to analyze these treatments based on the clinical and radiological outcome, iatrogenic effects, and pharmacological action.
Mots clés
Breast fibromatosis, Desmoid-type fibromatosis, Extra-abdominal fibromatosis, Sunitinib, Tyrosine-kinase inhibitors, Wnt-beta catenin
Référence
World J Surg Oncol. 2017 Apr;15(1):86