Plasma Renin Concentration is Associated with Hemodynamic Deficiency and Adverse Renal Outcome in Septic Shock.
Fiche publication
Date publication
novembre 2018
Journal
Shock (Augusta, Ga.)
Auteurs
Membres identifiés du Cancéropôle Est :
Pr DUVILLARD Laurence
Tous les auteurs :
Nguyen M, Denimal D, Dargent A, Guinot PG, Duvillard L, Quenot JP, Bouhemad B
Lien Pubmed
Résumé
In septic shock, both systemic vasodilatation and glomerular arteriole dilatation are responsible for the drop in glomerular filtration observed in early acute kidney injury. Angiotensin II has been showed to act on both mechanisms. Our objective was to evaluate the impact of renin angiotensin system activation, on hemodynamic deficiency and renal outcome in patient with septic shock and to assess whether urinary sodium could be a reliable test for high plasma renin concentration screening.
Référence
Shock. 2018 Nov 6;: