Encapsulation of S-nitrosoglutathione: a transcriptomic validation.
Fiche publication
Date publication
novembre 2018
Journal
Drug development and industrial pharmacy
Auteurs
Membres identifiés du Cancéropôle Est :
Dr DUBOIS-POT-SCHNEIDER Hélène, Dr HOULGATTE Rémy, Pr RIHN Bertrand
Tous les auteurs :
Safar R, Houlgatte R, Le Faou A, Ronzani C, Wu W, Ferrari L, Dubois-Pot-Schneider H, Rihn BH, Joubert O
Lien Pubmed
Résumé
S-nitrosogluthatione (GSNO), a S-nitrosothiol, is a commonly used as nitric oxide (NO) donor. However, its half-life is too short for a direct therapeutic use. To protect and ensure a sustained release of NO, the encapsulation of GSNO into nanoparticles may be an interesting option.
Mots clés
-nitrosoglutathione, monocytes, nitric oxide, polymeric nanoparticles, transcriptome
Référence
Drug Dev Ind Pharm. 2018 Nov 17;:1-28