Synergistic Mechano-Chemical Sensing by Vascular Cilia.
Fiche publication
Date publication
juillet 2018
Journal
Trends in cell biology
Auteurs
Membres identifiés du Cancéropôle Est :
Dr GOETZ Jacky
Tous les auteurs :
Follain G, Goetz JG
Lien Pubmed
Résumé
Endothelial cells can sense and respond to blood flow forces and signals, but the exact mechanisms employed remain poorly understood. A recent study describes how low-flow forces are sensed by primary cilia during development of the retinal vasculature, which sensitizes endothelial cells to BMP signaling.
Mots clés
Cilia, Endothelial Cells, Signal Transduction
Référence
Trends Cell Biol.. 2018 Jul;28(7):507-508