Analytical dose modeling for preclinical proton irradiation of millimetric targets.
Fiche publication
Date publication
janvier 2018
Journal
Medical physics
Auteurs
Membres identifiés du Cancéropôle Est :
Dr BRASSE David, Dr FINCK Christian
Tous les auteurs :
Vanstalle M, Constanzo J, Karakaya Y, Finck C, Rousseau M, Brasse D
Lien Pubmed
Résumé
Due to the considerable development of proton radiotherapy, several proton platforms have emerged to irradiate small animals in order to study the biological effectiveness of proton radiation. A dedicated analytical treatment planning tool was developed in this study to accurately calculate the delivered dose given the specific constraints imposed by the small dimensions of the irradiated areas.
Mots clés
Animals, Computer Simulation, Mice, Monte Carlo Method, Neoplastic Cells, Circulating, Phantoms, Imaging, Proton Therapy, instrumentation, Protons, therapeutic use, Radiotherapy Dosage, Radiotherapy Planning, Computer-Assisted, instrumentation, Water
Référence
Med Phys. 2018 Jan;45(1):470-478