Sucrose octasulfate dressing versus control dressing in patients with neuroischaemic diabetic foot ulcers (Explorer): an international, multicentre, double-blind, randomised, controlled trial.
Fiche publication
Date publication
mars 2018
Journal
The lancet. Diabetes & endocrinology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr PETIT Jean-Michel
Tous les auteurs :
Edmonds M, Lázaro-Martínez JL, Alfayate-García JM, Martini J, Petit JM, Rayman G, Lobmann R, Uccioli L, Sauvadet A, Bohbot S, Kerihuel JC, Piaggesi A
Lien Pubmed
Résumé
Diabetic foot ulcers are serious and challenging wounds associated with high risk of infection and lower-limb amputation. Ulcers are deemed neuroischaemic if peripheral neuropathy and peripheral artery disease are both present. No satisfactory treatment for neuroischaemic ulcers currently exists, and no evidence supports one particular dressing. We aimed to assess the effect of a sucrose octasulfate dressing versus a control dressing on wound closure in patients with neuroischaemic diabetic foot ulcers.
Mots clés
Aged, Anti-Ulcer Agents, administration & dosage, Bandages, Diabetic Foot, therapy, Diabetic Neuropathies, therapy, Double-Blind Method, Female, Humans, International Agencies, Ischemia, therapy, Male, Prognosis, Sucrose, administration & dosage
Référence
Lancet Diabetes Endocrinol. 2018 03;6(3):186-196