Imaging thrombosis with Tc-labeled RAM.1-antibody in vivo.

Fiche publication


Date publication

mars 2018

Journal

Nuclear medicine and biology

Auteurs

Membres identifiés du Cancéropôle Est :
Dr BRASSE David, Pr LAQUERRIERE Patrice, Dr GACHET Christian


Tous les auteurs :
Ouadi A, Bekaert V, Receveur N, Thomas L, Lanza F, Marchand P, Gachet C, Mangin PH, Brasse D, Laquerriere P

Résumé

Platelets play a major role in thrombo-embolic diseases, notably by forming a thrombus that can ultimately occlude a vessel. This may provoke ischemic pathologies such as myocardial infarction, stroke or peripheral artery diseases, which represent the major causes of death worldwide. The aim of this study was to evaluate the specificity of radiolabeled Rat-Anti-Mouse antibody (RAM.1).

Mots clés

Antibodies, Platelets, Single-photon emission computed tomography, Thrombosis

Référence

Nucl. Med. Biol.. 2018 Mar 17;61:21-27