Molecular features of Hepatitis E Virus circulation in environmental and human samples.

Fiche publication


Date publication

avril 2018

Journal

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology

Auteurs

Membres identifiés du Cancéropôle Est :
Pr BRONOWICKI Jean-Pierre, Dr JEULIN Hélène


Tous les auteurs :
Fenaux H, Chassaing M, Berger S, Jeulin H, Gentilhomme A, Bensenane M, Bronowicki JP, Gantzer C, Bertrand I, Schvoerer E

Résumé

Hepatitis E virus (HEV) is emerging but its circulation between humans and the environment remains misunderstood. HEV ORF2 gene encodes the capsid playing a key role in viral interactions with surfaces, ORF3 products are involved in the viral cycle. Our aim was to study the molecular characteristics of ORF2 and ORF3 which could favor HEV fitness in patients and the environment.

Mots clés

Hepatitis E virus, Transmission, Ultra-deep sequencing, Variability

Référence

J. Clin. Virol.. 2018 Apr 5;103:63-70