[Base of the skull meningioma: Efficacy, clinical tolerance and radiological evaluation after radiotherapy].
Fiche publication
Date publication
mai 2018
Journal
Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
Auteurs
Membres identifiés du Cancéropôle Est :
Pr ANTONI Delphine, Pr NOEL Georges, Dr CEBULA Hélène, Pr PROUST François
Tous les auteurs :
Brahimi Y, Antoni D, Srour R, Proust F, Cebula H, Labani A, Noël G
Lien Pubmed
Résumé
Skull base meningioma leads to functional disturbances, which can significantly alter the quality of life. The optimal management of these lesions, whose goals are neurological preservation and tumour local control, is not yet clearly established. It is widely recognized that the goal of a radical excision should be abandoned despite the advances in the field of microsurgery of skull base lesions. Although less morbid, partial tumour excision would be associated with increased risk of local tumour recurrence. Although discussed both exclusive and adjuvant have proven to be highly successful in terms of clinical improvement and local control. Various radiation techniques have demonstrated their efficacy in the management of this pathology. However, high rates of clinical improvement are in contrast with low rates of radiological improvement. The notion of clinical and radiological dissociation appeared. However, in most of these studies, the analysis of the radiological response could be subject of legitimate criticism. This work proposes to review the local control, the efficacy and the clinical tolerance and the radiological response of the various radiation techniques for the meningioma of the base of the skull and to demonstrate the interest of quantitative volumetric analyses in the follow-up of meningioma after radiotherapy.
Mots clés
Analyse volumétrique, Base du crâne, Intensity-modulated radiation therapy, Meningioma, Méningiome, RCMI, Radiochirurgie, Radiothérapie stéréotaxique, Résultat thérapeutique, Skull base, Stereotactic radiation, Volumetric analyses
Référence
Cancer Radiother. 2018 May 14;: