[Anal canal cancer: In the era of intensity-modulated radiotherapy, outstanding issues].
Fiche publication
Date publication
septembre 2018
Journal
Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
Auteurs
Membres identifiés du Cancéropôle Est :
Pr PEIFFERT Didier, Dr FAIVRE Jean-Christophe
Tous les auteurs :
Peiffert D, Baumann AS, Serre AA, Vendrely V, Rouard N, Faivre JC, Vogin G
Lien Pubmed
Résumé
Intensity-modulated radiotherapy makes possible to optimize the irradiation and spare normal tissues. The toxicity remains important with concomitant chemotherapy often associated. The improvement of MRI and PET-CT define more precisely the target volumes, which need a higher dose, but necessitates to respect the rules of contouring. The treatment is uniform whatever the stage but should be individualized based on clinical stage and tumor response. New paradigms concern biology, staging, volumes and doses, fractionation and combined treatments.
Mots clés
Anal cancer, Brachytherapy, Cancer anal, Chemoradiotherapy, Chimioradiothérapie, Clinical trials, Curiethérapie, Delineation, Délinéation, Essais cliniques, IMRT, RCMI
Référence
Cancer Radiother. 2018 Sep 1;: