[Hypofractioned radiotherapy in elderly patient with glioblastoma].

Fiche publication


Date publication

septembre 2018

Journal

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique

Auteurs

Membres identifiés du Cancéropôle Est :
Pr ANTONI Delphine, Pr NOEL Georges


Tous les auteurs :
Kuntz L, Noel G, Antoni D

Résumé

Glioblastoma is the most frequent primary brain tumor, with more than half of all patients being at least 65 years old. The treatment of the elderly in this pathology represents therefore a considerable challenge for oncologists and radiation therapists. However, in most clinical trials, age is a non-eligible criterial. In the last ten years, geriatric therapeutic trials have been multiplied. The treatment of glioblastoma consists of adjuvant chemoradiotherapy. In elderly patients, the evaluation of performans status and the molecular characteristics of the tumor are important factors in order to propose the appropriate treatment in terms of efficacy and toxicity.

Mots clés

Elderly, Glioblastoma, Glioblastome, Hypofractionated radiotherapy, Personnes âgées, Radiothérapie hypofractionée, Temozolomide, Témozolomide

Référence

Cancer Radiother. 2018 Sep 6;: