Use of the slope of the DVH curve for predicting late rectal toxicity in IMRT for patients with localized prostate cancer.
Fiche publication
Date publication
février 2012
Journal
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Auteurs
Membres identifiés du Cancéropôle Est :
Dr MARTIN Etienne, Dr MIRJOLET Céline
Tous les auteurs :
Crehange G, Walker PM, Gauthier M, Mirjolet-Didelot C, Petitfils A, Martin E, Chamois J, Khoury C, Maingon P
Lien Pubmed
Résumé
230 Background: Dose volume specific endpoints (DVSE) have been demonstrated to be reliable and reproducible for predicting late toxicity with conformal 3D-RT. New highly sophisticated delivery techniques such as IGRT or IMRT or combined IG-IMRT can spare rectum more efficiently while substantially increasing the delivered dose to the prostate. The purpose of this study is to investigate whether the slope of the DVH curve could predict late rectal toxicity more accurately than DVSE in prostate cancer (PCa) patients.
Référence
J. Clin. Oncol.. 2012 Feb;30(5_suppl):230