Radiation plus docetaxel and cisplatin in locally advanced pancreatic carcinoma: a non-comparative randomized phase II trial.
Fiche publication
Date publication
octobre 2014
Journal
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
Auteurs
Membres identifiés du Cancéropôle Est :
Pr CONROY Thierry, Pr PEIFFERT Didier
Tous les auteurs :
Ducreux M, Giovannini M, Baey C, Llacer C, Bennouna J, Adenis A, Peiffert D, Mornex F, Abbas M, Boige V, Pignon JP, Conroy T, Cellier P, Juzyna B, Viret F
Lien Pubmed
Résumé
We performed a randomized, non-comparative phase II study evaluating docetaxel in combination with either daily continuous (protracted IV) 5-fluorouracil or cisplatin administered weekly, concurrent to radiotherapy in the treatment of locally advanced pancreatic carcinoma. Results of the docetaxel plus cisplatin regimen are reported.
Mots clés
Adolescent, Adult, Aged, Antineoplastic Agents, administration & dosage, Antineoplastic Combined Chemotherapy Protocols, therapeutic use, Chemoradiotherapy, Cisplatin, administration & dosage, Drug Administration Schedule, Female, Fluorouracil, administration & dosage, Humans, Male, Middle Aged, Pancreatic Neoplasms, mortality, Survival Analysis, Taxoids, administration & dosage, Treatment Outcome, Young Adult
Référence
Dig Liver Dis. 2014 Oct;46(10):950-5