Markov modelling of HIV infection evolution in the HAART era.
Fiche publication
Date publication
septembre 2009
Auteurs
Membres identifiés du Cancéropôle Est :
Pr BINQUET Christine, Pr QUANTIN Catherine
Tous les auteurs :
Binquet C, Le Teuff G, Abrahamovicz M, Mahboubi A, Yazdanpanah Y, Rey D, Rabaud C, Chirouze C, Berger JL, Faller JP, Chavanet P, Quantin C, Piroth L
Lien Pubmed
Résumé
The aim was to investigate the impact of the main prognostic factors on HIV evolution. A multi-state Markov model was applied in a cohort of 2126 patients to estimate impact of these factors on patients' clinical and immunological evolutions. Clinical progression and immunological deterioration shared most of their prognostic factors: male gender, intravenous drug use, weight loss, low haemoglobin level (
Référence
Epidemiol Infect. 2009 Sep;137(9):1272-82