Photosensitivity associated with selective serotonin reuptake inhibitors.
Fiche publication
Date publication
décembre 2009
Auteurs
Membres identifiés du Cancéropôle Est :
Dr DALAC Sophie
Tous les auteurs :
Doffoel-Hantz V, Boulitrop-Morvan C, Sparsa A, Bonnetblanc JM, Dalac S, Bedane C
Lien Pubmed
Résumé
Selective serotonin reuptake inhibitors (SSRIs) are a widely prescribed group of antidepressants. We report three cases of photosensitivity induced by fluvoxamine and paroxetine. These photoallergic reactions suggest cross-reactivity between different molecules. Methylation metabolism could explain common photosensitization. Although these drugs are widely prescribed, such photosensitization is rare. Nevertheless, we consider that clinicians and patients should be aware of the risk of photosensitization and these drugs should be stopped before phototherapy or prolonged sun exposure.
Référence
Clin Exp Dermatol. 2009 Dec;34(8):e763-5