Successful treatment of a granulocytic sarcoma of the uterine cervix in complete remission at six-year follow-up.

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Date publication

janvier 2010

Auteurs

Membres identifiés du Cancéropôle Est :
Pr CHENARD Marie-Pierre, Pr HERBRECHT Raoul, Dr LIOURE Bruno


Tous les auteurs :
Kim SC, Natarajan-Ame S, Lioure B, Chenard MP, Duclos B, Herbrecht R, Bergerat JP

Résumé

Background. Localized granulocytic sarcoma of the uterine cervix in the absence of acute myelogenous leukemia (AML) at presentation is very rare, its diagnosis is often delayed, and its prognosis almost always ominous evolving into refractory AML. Case. We present the case of a 30-year-old woman with vaginal bleeding and a large cervical mass. Further evaluation confirmed the presence of a granulocytic sarcoma but failed to reveal systemic involvement. Results. AML type chemotherapy followed by radiotherapy of the uterus led to a durable complete remission. She remains in complete remission six years after diagnosis. Conclusion. Granulocytic sarcoma of the cervix is a rare entity for which early intensive AML type therapy is effective.

Référence

J Oncol. 2010;2010:812424