Détail d'une personne de l'annuaire - fr | Cancéropôle Est, la recherche innovante dans la lutte contre le cancer

Expressions of HuR, Methyl-HuR and Phospho-HuR in Endometrial Endometrioid Adenocarcinoma Are Associated with Clinical Features.

Hotton J, Gauchotte G, Mougel R, Migliorini M, Lacomme S, Battaglia-Hsu SF, Agopiantz M

Int J Mol Sci. 2024 01 12;25(2):

MicroRNAs miR-16 and miR-519 control meningioma cell proliferation overlapping transcriptomic programs shared with the RNA-binding protein HuR.

Hergalant S, Casse JM, Oussalah A, Houlgatte R, Helle D, Rech F, Vallar L, Guéant JL, Vignaud JM, Battaglia-Hsu SF, Gauchotte G

Front Oncol. 2023 08 2;13:1158773

A High MCM6 Proliferative Index in Atypical Meningioma Is Associated with Shorter Progression Free and Overall Survivals.

Gauchotte G, Bédel C, Lardenois E, Hergalant S, Cuglietta L, Pflaum R, Lacomme S, Pina H, Treffel M, Rech F, Battaglia-Hsu SF

Cancers (Basel). 2023 01 16;15(2):

Correlation between DNA Methylation and Cell Proliferation Identifies New Candidate Predictive Markers in Meningioma.

Hergalant S, Saurel C, Divoux M, Rech F, Pouget C, Godfraind C, Rouyer P, Lacomme S, Battaglia-Hsu SF, Gauchotte G

Cancers (Basel). 2022 12 17;14(24):

Knockout in U251 Glioblastoma Cells Reduces Tumor Sphere Formation by Increasing Oxidative Stress and Suppressing Methionine Dependency.

Quéré M, Alberto JM, Broly F, Hergalant S, Christov C, Gauchotte G, Guéant JL, Namour F, Battaglia-Hsu SF

Nutrients. 2022 04 30;14(9):

S-adenosylmethionine upregulates the angiotensin receptor-binding protein ATRAP via the methylation of HuR in NAFLD.

Guo T, Dai Z, You K, Battaglia-Hsu SF, Feng J, Wang F, Li B, Yang J, Li Z

Cell Death Dis. 2021 Mar 22;12(4):306

LINC00662 promotes hepatocellular carcinoma progression via altering genomic methylation profiles.

Guo T, Gong C, Wu P, Battaglia-Hsu SF, Feng J, Liu P, Wang H, Guo D, Yao Y, Chen B, Xiao Y, Liu Z, Li Z

Cell Death Differ.. 2020 Jan 20;:

SIRT1 activation rescues the mislocalization of RNA-binding proteins and cognitive defects induced by inherited cobalamin disorders.

Ghemrawi R, Arnold C, Battaglia-Hsu SF, Pourié G, Trinh I, Bassila C, Charif R, Wiedemann A, Flayac J, Robert A, Dreumont N, Feillet F, Guéant JL, Coelho D

Metab. Clin. Exp.. 2019 Oct 28;:153992

Ki-67 and MCM6 labelling indices are correlated with overall survival in anaplastic oligodendroglioma, IDH1-mutant and 1p/19q-codeleted: a multicenter study from the French POLA network.

Pouget C, Hergalant S, Lardenois E, Lacomme S, Houlgatte R, Carpentier C, Dehais C, Rech F, Taillandier L, Sanson M, Appay R, Colin C, Figarella-Branger D, Battaglia-Hsu SF, Gauchotte G,

Brain Pathol.. 2019 Sep 27;:

Folate can promote the methionine-dependent reprogramming of glioblastoma cells towards pluripotency.

Zgheib R, Battaglia-Hsu SF, Hergalant S, Quéré M, Alberto JM, Chéry C, Rouyer P, Gauchotte G, Guéant JL, Namour F

Cell Death Dis. 2019 Aug 8;10(8):596

COPPS, a composite score integrating pathological features, PS100 and SDHB losses, predicts the risk of metastasis and progression-free survival in pheochromocytomas/paragangliomas.

Pierre C, Agopiantz M, Brunaud L, Battaglia-Hsu SF, Max A, Pouget C, Nomine C, Lomazzi S, Vignaud JM, Weryha G, Oussalah A, Gauchotte G, Busby-Venner H

Virchows Arch.. 2019 Mar 13;:

Inherited disorders of cobalamin metabolism disrupt nucleocytoplasmic transport of mRNA through impaired methylation/phosphorylation of ELAVL1/HuR.

Battaglia-Hsu SF, Ghemrawi R, Coelho D, Dreumont N, Mosca P, Hergalant S, Gauchotte G, Sequeira JM, Ndiongue M, Houlgatte R, Alberto JM, Umoret R, Robert A, Paoli J, Jung M, Quadros EV, Guéant JL

Nucleic Acids Res.. 2018 Jul 17;:

Endoplasmic Reticulum Stress in Metabolic Disorders.

Ghemrawi R, Battaglia-Hsu SF, Arnold C

Cells. 2018 Jun 19;7(6):

Minichromosome maintenance complex component 6 (MCM6) expression correlates with histological grade and survival in endometrioid endometrial adenocarcinoma.

Hotton J, Agopiantz M, Leroux A, Charra-Brunaud C, Marie B, Busby-Venner H, Morel O, Guéant JL, Vignaud JM, Battaglia-Hsu SF, Gauchotte G

Virchows Arch.. 2018 Apr;472(4):623-633

Post-transcriptional regulation of cytokine in the context of renal inflammation.

Feigerlová E, Battaglia-Hsu SF

Minerva Med.. 2017 Dec;108(6):518-526

IL-6 signaling in diabetic nephropathy: From pathophysiology to therapeutic perspectives.

Feigerlová E, Battaglia-Hsu SF

Cytokine Growth Factor Rev.. 2017 Oct;37:57-65

Extracellular vesicles as immune mediators in response to kidney injury.

Feigerlova E, Battaglia-Hsu SF, Hauet T, Guéant JL

Am. J. Physiol. Renal Physiol.. 2017 Aug;:ajprenal.00336.2017

Cytoplasmic overexpression of RNA-binding protein HuR is a marker of poor prognosis in meningioma, and HuR knockdown decreases meningioma cell growth and resistance to hypoxia.

Gauchotte G, Hergalant S, Vigouroux C, Casse JM, Houlgatte R, Kaoma T, Helle D, Brochin L, Rech F, Peyre M, Labrousse F, Vallar L, Gueant JL, Vignaud JM, Battaglia-Hsu SF

J. Pathol.. 2017 May;:

Role of post-transcriptional regulation of mRNA stability in renal pathophysiology: focus on chronic kidney disease.

Feigerlová E, Battaglia-Hsu SF

FASEB J.. 2017 02;31(2):457-468

Cytokines in Endocrine Dysfunction of Plasma Cell Disorders.

Feigerlová E, Battaglia-Hsu SF

Mediators Inflamm.. 2017 ;2017:7586174

30 months follow-up of an early enzyme replacement therapy in a severe Morquio A patient: About one case.

Do Cao J, Wiedemann A, Quinaux T, Battaglia-Hsu SF, Mainard L, Froissart R, Bonnemains C, Ragot S, Leheup B, Journeau P, Feillet F

Mol Genet Metab Rep. 2016 Dec;9:42-45

Methyl donor deficiency impairs bone development via peroxisome proliferator-activated receptor-γ coactivator-1α-dependent vitamin D receptor pathway.

Feigerlova E, Demarquet L, Melhem H, Ghemrawi R, Battaglia-Hsu SF, Ewu E, Alberto JM, Helle D, Weryha G, Guéant JL

FASEB J.. 2016 Oct;30(10):3598-3612

Genotype-phenotype associations in French patients with phenylketonuria and importance of genotype for full assessment of tetrahydrobiopterin responsiveness.

Jeannesson-Thivisol E, Feillet F, Chéry C, Perrin P, Battaglia-Hsu SF, Herbeth B, Cano A, Barth M, Fouilhoux A, Mention K, Labarthe F, Arnoux JB, Maillot F, Lenaerts C, Dumesnil C, Wagner K, Terral D, Broué P, de Parscau L, Gay C, Kuster A, Bédu A, Besson G, Lamireau D, Odent S, Masurel A, Guéant JL, Namour F

Orphanet J Rare Dis. 2015 Dec;10:158

In malignant cartilagenous tumors, immunohistochemical expression of procollagen PC1CP peptide is higher and that of PC2CP lower than in benign cartilaginous lesions.

Delaunay-Lemarie C, Vincourt JB, Marie B, Battaglia-Hsu SF, Etienne S, Sirveaux F, Nguyen Thi PL, Magdalou J, Vignaud JM, Gauchotte G

Virchows Arch. 2015 Sep;467(3):329-37

Methyl(R217)HuR and MCM6 are inversely correlated and are prognostic markers in non small cell lung carcinoma.

Vigouroux C, Casse JM, Battaglia-Hsu SF, Brochin L, Luc A, Paris C, Lacomme S, Gueant JL, Vignaud JM, Gauchotte G

Lung Cancer. 2015 May 16. pii: S0169-5002(15)00244-5

Methyl-deficient diet promotes colitis and SIRT1-mediated endoplasmic reticulum stress.

Melhem H, Hansmannel F, Bressenot A, Battaglia-Hsu SF, Billioud V, Alberto JM, Gueant JL, Peyrin-Biroulet L

Gut. 2015 Jan 20. pii: gutjnl-2014-307030

Molecular and cellular effects of vitamin B12 in brain, myocardium and liver through its role as co-factor of methionine synthase.

Gueant JL, Caillerez-Fofou M, Battaglia-Hsu S, Alberto JM, Freund JN, Dulluc I, Adjalla C, Maury F, Merle C, Nicolas JP, Namour F, Daval JL

Biochimie. 2013 May;95(5):1033-40

Decreased vitamin B12 availability induces ER stress through impaired SIRT1-deacetylation of HSF1.

Ghemrawi R, Pooya S, Lorentz S, Gauchotte G, Arnold C, Gueant JL, Battaglia-Hsu SF

Cell Death Dis. 2013 Mar 21;4:e553

Undiagnosed phenylketonuria in parents of phenylketonuric patients, is it worthwhile to be checked?

Wiedemann A, Leheup B, Battaglia-Hsu SF, Jonveaux P, Jeannesson E, Feillet F

Mol Genet Metab. 2013;110 Suppl:S62-5

Expression of minichromosome maintenance MCM6 protein in meningiomas is strongly correlated with histologic grade and clinical outcome.

Gauchotte G, Vigouroux C, Rech F, Battaglia-Hsu SF, Soudant M, Pinelli C, Civit T, Taillandier L, Vignaud JM, Bressenot A

Am J Surg Pathol. 2012 Feb;36(2):283-91.

Association of IL1B polymorphism with left ventricular systolic dysfunction: a relation with the release of interleukin-1beta in stress condition.

Gueant-Rodriguez RM, Juilliere Y, Battaglia-Hsu SF, Debard R, Gerard P, Reyes P, Danchin N, Gueant JL

Pharmacogenet Genomics. 2011 Sep;21(9):579-86.

Vitamin B12 deficiency reduces proliferation and promotes differentiation of neuroblastoma cells and up-regulates PP2A, proNGF, and TACE.

Battaglia-Hsu SF, Akchiche N, Noel N, Alberto JM, Jeannesson E, Orozco-Barrios CE, Martinez-Fong D, Daval JL, Gueant JL

Proc Natl Acad Sci U S A. 2009 Dec 22;106(51):21930-5

Anchoring secreted proteins in endoplasmic reticulum by plant oleosin: the example of vitamin B12 cellular sequestration by transcobalamin.

Pons L, Battaglia-Hsu SF, Orozco-Barrios CE, Ortiou S, Chery C, Alberto JM, Arango-Rodriguez ML, Dumas D, Martinez-Fong D, Freund JN, Gueant JL

PLoS One. 2009 Jul 22;4(7):e6325.

Signalling with retinoids in the human lung: validation of new tools for the expression study of retinoid receptors.

Poulain S, Lacomme S, Battaglia-Hsu SF, du Manoir S, Brochin L, Vignaud JM, Martinet N

BMC Cancer. 2009 Dec 4;9:423.

Vitamin B12-impaired metabolism produces apoptosis and Parkinson phenotype in rats expressing the transcobalamin-oleosin chimera in substantia nigra.

Orozco-Barrios CE, Battaglia-Hsu SF, Arango-Rodriguez ML, Ayala-Davila J, Chery C, Alberto JM, Schroeder H, Daval JL, Martinez-Fong D, Gueant JL

PLoS One. 2009 Dec 21;4(12):e8268.

Evidence of cataplerosis in a patient with neonatal classical galactosemia presenting as citrin deficiency.

Feillet F, Merten M, Battaglia-Hsu SF, Rabier D, Kobayashi K, Straczek J, Brivet M, Favre E, Gueant JL

J Hepatol. 2008 Mar;48(3):517-22

Dr BATTAGLIA-HSU Shyue-Fang

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